Healthy Aging
As lifespans increase, consumer demand for products that promote healthy aging has intensified. INQUIS Clinical Research is proud to provide services to the industry to help establish benefits of their products as they relate to aging.
The interconnectedness among aging, cognition, and disease risk factors is well-established, with a solid connection to nutrition. At INQUIS Clinical Research, our team of researchers will design and execute studies that demonstrate the effect of your food product on cognitive function, including memory.
Contact us to learn how we can help you achieve your clinical research objectives.
Kaplan RJ, Greenwood CE, Winocur G, Wolever TM. Dietary protein, carbohydrate, and fat enhance memory performance in the healthy elderly. Am J Clin Nutr 2001;74(5):687-93.
Kaplan RJ, Greenwood CE, Winocur G, Wolever TM. Cognitive performance is associated with glucose regulation in healthy elderly persons and can be enhanced with glucose and dietary carbohydrates. Am J Clin Nutr 2000;72(3):825-36.
Through quality of life questionnaires and assessments of mood, mobility, and energy, we can examine the effect of your product on an aging population.
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Wolever TMS, Chiasson J-L, Josse RG, Leiter LA, Maheux P, Rabasa-Lhoret R, Rodger NW, Ryan EA. Effects of changing the amount and source of dietary carbohydrates on symptoms and dietary satisfaction over a 1-year period in subjects with type 2 diabetes: Canadian trial of carbohydrates in diabetes (CCD). Can J Diab 2017;41:164-76.
Chui MH, Papanikolaou Y, Fontaine-Bisson B, Turcotte J, Wolever TM, El-Sohemy A, Chiasson JL, Rabasa-Lhoret R, Maheux P, Ryan E, Greenwood CE. The TNF-alpha-238G > a single-nucleotide polymorphism protects against memory decline in older adults with type 2 diabetes. Behav Neurosci 2007;121(3):619-24.
With aging, the ability to mount an immune response tends to decrease. Dietary factors, probiotics, and natural health products can play a role in maintaining or enhancing immune functions. At INQUIS Clinical Research, we help design studies that measure modulation of immune response in target populations either through direct measurement of immunoglobulins such as IgA and IgE or by measurement of symptoms in response to an appropriate stressor.
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Ghorbani P, Santhakumar P, Hu Q, Dijadeu P, Wolever TM, Palaniyar N, Grasemann H. Short-chain fatty acids affect cystic fibrosis airway inflammation and bacterial growth. Eur Respir J. @015 Oct; 46(4):1033-45.
Belcheva A, Irrazabal T, Robertson SJ, Streutker C, Maughan H, Rubino S, Moriyama EH, Copeland JK, Surendra A, Kumar S, Green B, Geddes K, Pezo RC, Navarre WW, Milosevic M, Wilson BC, Girardin SE, Wolever TMS, Edelmann W, Guttman DS, Philpott DJ, Martin A. Gut microbial metabolism drives transformation of MHS2-deficient colon epithelial cells. Cell. 2014 Jul 17; 158(2):288-289.
INQUIS Clinical Research offers a complete suite of services to help you structure your trial from end to end. We ensure you receive a custom-designed program that covers every aspect of your research needs seamlessly from beginning to end. We can partner as intensively as needed for clients who require our expertise with only some aspects of their clinical trial.
Features of our clinical trial services include:
