Our team at INQUIS recently conducted a long-term cholesterol-lowering trial in close to 200 research participants. In addition to the cholesterol-lowering effects that were detected in beverages containing oat beta-glucan, we also found significant effects in non-GI symptoms, such as headache and fatigue, as well as joint and limb pain, after participants consumed beverages containing oat beta-glucan daily for 4 weeks.

“These results were really very exciting to us,” says Dr. Thomas Wolever, Principal Scientist and Medical Director at INQUIS Clinical Research. “In addition to finding reductions in LDL cholesterol and a lowering of Framingham CVD risk, we also found significant changes in participants’ feelings of wellness, as indicated by anxiety and headache, as well as feeling cold. Fatigue and joint/limb pain also tended to decrease. The severity of symptoms related to general well-being are an important piece of the puzzle in the clinical research we do. These symptoms can be just as important as markers of disease, because they directly impact quality of life. In addition, if participants are generally feeling better, they are more likely to continue to consume a product that is healthier for them.”

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