Time in Range

March 2022

Time in Range (TIR) is a relatively new metric that tracks the amount of time a person’s blood glucose levels remain within a target blood glucose range (70-180 mg/dL or 3.9-10.0 mmol/L). TIR is assessed using Continuous Glucose Monitoring (CGM). It complements other measures like HbA1c, by giving a more detailed view of daily glucose excursions and detecting glucose variations and hypoglycemic events. When using CGM, other metrics can also be assessed, such as mean glucose concentration, glycemic variability, and Mean Amplitude of Glycemic Excursions (MAGE).

“Time in Range is useful because it provides a more complete picture of glucose excursions,” says Dr. Thomas Wolever, Principal Scientist and Medical Director at INQUIS. “It helps us see on a very granular level the effect of a particular food, ingredient, or diet plan on daily glucose fluctuations, which we know is an important priority for people living with diabetes and pre-diabetes. With the availability of continuous glucose monitors and their extensive technological compatibilities, our research participants are able to go about their day-to-day lives wearing the monitors, providing real-life measurement of the effect of the product being studied.”